CareLit · DOI-Nachweis · Pneumologie
Genome-wide chromatin profiling of Legionella pneumophila-infected human macrophages reveals activation of the pro-bacterial host factor TNFAIP2
DOI 10.1055/s-0036-1584629
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Autor:innenI DuBois, A Marsico, W Bertrams, A Sittka-Stark, B Caffrey, M Schweiger, M Eberhardt, J Vera, M Vingron, B Schmeck
ZeitschriftPneumologie
Ausgabe07/2016
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Introduction: Legionella pneumophila (L. pneumophila) is a causative agent of severe pneumonia. Infection leads to a broad host cell response, as evident e.g. on the transcriptional level. Chromatin modifications, which control gene expression, play a central role in the transcriptional response to L. pneumophila. Methods: We infected human blood-derived macrophages with L. pneumophila and used chromatin immunopreci…
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Zitierempfehlung
I DuBois, A Marsico, W Bertrams, A Sittka-Stark, B Caffrey, M Schweiger, M Eberhardt, J Vera, M Vingron, B Schmeck (2016) Genome-wide chromatin profiling of Legionella pneumophila-infected human macrophages reveals activation of the pro-bacterial host factor TNFAIP2. Pneumologie (07). https://doi.org/10.1055/s-0036-1584629
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