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Cigarette Smoke and Cigarette Smoke Condensate Induce Inflammation and Cytotoxicity in Precision-Cut Lung Slices (PCLS)

H Obernolte, D Ritter, J Knebel, P Braubach, D Jonigk, G Warnecke, M Krüger, HG Fieguth, O Pfennig, A Braun, K Sewald · Pneumologie · Ausgabe 07/2016

DOI 10.1055/s-0036-1584646

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Nachweis in CareLit

Autor:innenH Obernolte, D Ritter, J Knebel, P Braubach, D Jonigk, G Warnecke, M Krüger, HG Fieguth, O Pfennig, A Braun, K Sewald
ZeitschriftPneumologie
Ausgabe07/2016
Jahrgang / SeitenNicht angegeben

Kernaussage aus der Literatur

Abstract-Vorschau

COPD is characterised by emphysema, mucus hypersecretion and airway inflammation. COPD is the fourth leading cause of death worldwide. Major reason to develop COPD is cigarette smoke (Cs). Therefore, a human relevant Cs model is needed. Currently several human cell culture models and non-human animal models are well-established. Most are lacking the human microenvironment, which is necessary to induce inflammatory,…

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Zitierempfehlung

H Obernolte, D Ritter, J Knebel, P Braubach, D Jonigk, G Warnecke, M Krüger, HG Fieguth, O Pfennig, A Braun, K Sewald (2016) Cigarette Smoke and Cigarette Smoke Condensate Induce Inflammation and Cytotoxicity in Precision-Cut Lung Slices (PCLS). Pneumologie (07). https://doi.org/10.1055/s-0036-1584646

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