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Secretion of miRNA-containing extracellular vesicles (EV) by bronchial epithelial cells in allergic airway inflammation

S Bartel, AC Schamberger, O Eickelberg, S Krauss-Etschmann · Pneumologie · Ausgabe 07/2016

DOI 10.1055/s-0036-1584653

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Autor:innenS Bartel, AC Schamberger, O Eickelberg, S Krauss-Etschmann
ZeitschriftPneumologie
Ausgabe07/2016
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Background: miRNAs (miR) are critical regulators of the immune system. Recently they have been shown to be secreted into EVs for inter-cell communication (Valadi et al., Nat Cell Biol, 2007). We previously identified an up-regulation of miR-17 and -21 in murine lung homogenate in Ovalbumin (OVA) induced allergic airway inflammation (AAI). Objective: We now asked if mir-17 and miR-21 are produced by the human bronchi…

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S Bartel, AC Schamberger, O Eickelberg, S Krauss-Etschmann (2016) Secretion of miRNA-containing extracellular vesicles (EV) by bronchial epithelial cells in allergic airway inflammation. Pneumologie (07). https://doi.org/10.1055/s-0036-1584653

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