CareLit · DOI-Nachweis · Pneumologie
Intravital microscopy of mucus transport in mice provides mechanistic insight into hypertonic saline treatment of Cystic Fibrosis
DOI 10.1055/s-0036-1584654
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Nachweis in CareLit
Autor:innenM Pieper, H Schulz-Hildebrandt, M Mall, G Hüttmann, P König
ZeitschriftPneumologie
Ausgabe07/2016
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
In clinical studies of cystic fibrosis (CF) patients, inhalation of 7% NaCl was found to be superior compared to 0.9%, which is attributed to increased hydration of mucus. However, mechanistic insight has been hampered by the inability to visualize mucus transport in vivo with microscopic resolution. To overcome this problem we developed a custom-built optical coherence microscope (OCM) providing a microscopic resol…
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Zitierempfehlung
M Pieper, H Schulz-Hildebrandt, M Mall, G Hüttmann, P König (2016) Intravital microscopy of mucus transport in mice provides mechanistic insight into hypertonic saline treatment of Cystic Fibrosis. Pneumologie (07). https://doi.org/10.1055/s-0036-1584654
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