CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
In vivo cell specific gene silencing in the liver using novel siRNA-loaded biodegradable nanohydrogel particles
DOI 10.1055/s-0036-1586951
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Autor:innenD Schuppan
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2016
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Background: Efficient in vivo transport of active siRNA to specific liver cells remains challenging. We have designed a new generation of NHP (bio-NHP), this time with biodegradable and ameliorated biocompatibility properties compared to the recent published NHP [Kaps L et al, Adv. Health. care mat.], that show promising in vitro and in vivo performance in one-on-one studies to NHP. Bio-NHP exhibit all NHP's positiv…
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Zitierempfehlung
D Schuppan (2016) In vivo cell specific gene silencing in the liver using novel siRNA-loaded biodegradable nanohydrogel particles. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0036-1586951
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