CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Identification of novel Biomarkers for idiosyncratic drug-induced liver injury by combining MetaHeps® and Proteomics
DOI 10.1055/s-0036-1586971
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Nachweis in CareLit
Autor:innenA Benesic, D Dragoi, SM Ehrlich, G Pichler, NA Kulak, AL Gerbes
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2016
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Drug-induced liver injury (DILI) is the most frequent cause of acute liver failure and the single most important reason for regulatory actions on drugs. In contrast to dose-related hepatotoxicity, idiosyncratic DILI (iDILI) is not predictable by preclinical models. Diagnosis of iDILI relies on the exclusion of other causes for liver injury and it may be impossible to identify the causative agent in polym…
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Zitierempfehlung
A Benesic, D Dragoi, SM Ehrlich, G Pichler, NA Kulak, AL Gerbes (2016) Identification of novel Biomarkers for idiosyncratic drug-induced liver injury by combining MetaHeps® and Proteomics. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0036-1586971
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