CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The bile acid-phospholipid conjugate Ursodeoxycholyl Lysophosphatidylethanolamide (UDCA-LPE) disturbs pro-fibrogenic Integrin and TGFβ signaling
DOI 10.1055/s-0036-1587041
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Nachweis in CareLit
Autor:innenJ Su, H Gan-Schreier, W Chamulitrat, W Stremmel, A Pathil
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2016
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Integrin receptors, which are involved in cell-cell and cell-matrix interaction, emerge as crucial mediators of TGFβ1 activation in liver fibrosis and may therefore serve as attractive targets for anti-fibrogenic drug development. Ursodeoxycholyl Lysophosphatidylethanolamide (UDCA-LPE) is a synthetic bile acid-phospholipid conjugate with profound hepatoprotective and anti-fibrogenic functions in vitro an…
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Zitierempfehlung
J Su, H Gan-Schreier, W Chamulitrat, W Stremmel, A Pathil (2016) The bile acid-phospholipid conjugate Ursodeoxycholyl Lysophosphatidylethanolamide (UDCA-LPE) disturbs pro-fibrogenic Integrin and TGFβ signaling. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0036-1587041
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