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Tumor-initiating cells contribute to acquired chemoresistance during anti-angiogenic therapies in hepatocellular carcinoma

D Castven, C Czauderna, D Becker, D Wilhelm, MA Wörns, SS Thorgeirsson, P Grimminger, H Lang, PR Galle, JU Marquardt · Zeitschrift für Gastroenterologie · Ausgabe 08/2016

DOI 10.1055/s-0036-1587071

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Autor:innenD Castven, C Czauderna, D Becker, D Wilhelm, MA Wörns, SS Thorgeirsson, P Grimminger, H Lang, PR Galle, JU Marquardt
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2016
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Inhibition of neo-angiogenesis is an effective treatment strategy for advanced HCC. However, development of chemoresistance is observed in the majority of patients. Compelling evidence suggest that stem-like tumor-initiating cells (TICs) may contribute to the acquisition of resistant properties in many solid tumors, but their exact role in this process for HCC remains to be defined. Here, we evaluate the importance…

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Zitierempfehlung

D Castven, C Czauderna, D Becker, D Wilhelm, MA Wörns, SS Thorgeirsson, P Grimminger, H Lang, PR Galle, JU Marquardt (2016) Tumor-initiating cells contribute to acquired chemoresistance during anti-angiogenic therapies in hepatocellular carcinoma. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0036-1587071

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