CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Frequent polymorphism p.D19 H of the biliary cholesterol transporter ABCG5/8 increases the risk of gallstone disease in children
DOI 10.1055/s-0036-1587107
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Autor:innenM Krawczyk, O Niewiadomska, I Jankowska, K Jankowski, J Gozdowska, D Lebensztejn, S Wiecek, F Lammert, P Socha
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2016
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Genetic studies demonstrated that gallstones in adults are frequent in carriers of the p.D19 H variant in the hepatobiliary cholesterol transporter ABCG5/8. Presence of the Gilbert polymorphism in the UGT1A1 gene further increases this risk. The genetic background of common lithiasis in children has yet to be defined. Hence we investigated the role of the ABCG8 and UGT1A1*28 variants in the development…
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Zitierempfehlung
M Krawczyk, O Niewiadomska, I Jankowska, K Jankowski, J Gozdowska, D Lebensztejn, S Wiecek, F Lammert, P Socha (2016) Frequent polymorphism p.D19 H of the biliary cholesterol transporter ABCG5/8 increases the risk of gallstone disease in children. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0036-1587107
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