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A feasibility study to establish recruitment and immunmonitoring for a first in man study of a therapeutic H. pylori vaccine in healthy infected volunteers

K Straubinger, B Kalali, F Anderl, M Andree, L Hoffmann, C Bolz, T Kruse, A Werner, U Michaelis, C Brendel, M Vieth, M Roskrow, T Rösch, M Gerhard · Zeitschrift für Gastroenterologie · Ausgabe 08/2016

DOI 10.1055/s-0036-1587190

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Autor:innenK Straubinger, B Kalali, F Anderl, M Andree, L Hoffmann, C Bolz, T Kruse, A Werner, U Michaelis, C Brendel, M Vieth, M Roskrow, T Rösch, M Gerhard
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2016
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

H. pylori colonizes the stomach of about half of the world's population. The infection is acquired in early childhood and remains asymptomatic in the vast majority of infected individuals. Although the infection elicits a strong inflammatory response, the bacterium cannot be cleared by the immune system. This chronic infection is a prerequisite for the development of gastric adenocarcinomas, leading to considerable…

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K Straubinger, B Kalali, F Anderl, M Andree, L Hoffmann, C Bolz, T Kruse, A Werner, U Michaelis, C Brendel, M Vieth, M Roskrow, T Rösch, M Gerhard (2016) A feasibility study to establish recruitment and immunmonitoring for a first in man study of a therapeutic H. pylori vaccine in healthy infected volunteers. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0036-1587190

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