CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Human pluripotent stem cell-derived exocrine/ductal organoids generate human pancreas upon orthotopic transplantation and allow disease modelling
DOI 10.1055/s-0036-1587235
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Autor:innenM Hohwieler, A Illing, M Müller, Q Lin, A Lechel, J Rosendahl, T Seufferlein, M Wagner, A Kleger
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2016
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Exocrine/ductal pancreatic differentiation from human pluripotent stem cells is a poorly understood process albeit various diseases arise from this compartment. We designed a straightforward approach to direct human pluripotent stem cells (PSC) toward pancreatic organoids resembling exocrine and ductal progeny. Extensive phenotyping of the organoids not only shows the appropriate marker profile but also ultra-struct…
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Zitierempfehlung
M Hohwieler, A Illing, M Müller, Q Lin, A Lechel, J Rosendahl, T Seufferlein, M Wagner, A Kleger (2016) Human pluripotent stem cell-derived exocrine/ductal organoids generate human pancreas upon orthotopic transplantation and allow disease modelling. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0036-1587235
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