CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
p53 mediates persistent Stat3 activation and contributes to stromal reprogramming in pancreatic cancer in humans and mice
DOI 10.1055/s-0036-1587236
Bibliografische Angaben
Nachweis in CareLit
Autor:innenSM Wörmann, L Song, J Ai, N Diakopoulos, D Ruess, D Jodrell, O Sansom, T Hagemann, MP Protti, RM Schmid, M Lesina, H Algül
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2016
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Stromal reprogramming rather than stromal depletion is emerging as potential major target in patients with pancreatic ductal adenocarcinoma (PDAC). Increasing evidence suggests that persistent signal transducer and activator of transcription 3 (Stat3) activation is involved in the progression of various solid cancers. We hypothesize that functional loss of p53 mediates a new persistent activation-depende…
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Zitierempfehlung
SM Wörmann, L Song, J Ai, N Diakopoulos, D Ruess, D Jodrell, O Sansom, T Hagemann, MP Protti, RM Schmid, M Lesina, H Algül (2016) p53 mediates persistent Stat3 activation and contributes to stromal reprogramming in pancreatic cancer in humans and mice. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0036-1587236
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