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Sonoporation by microbubbles as gene therapy approach for liver cancer

L Rinaldi, G Franci, V Folliero, L Palomba, R Isticato, C Zannella, R Di Francia, I De Sio, LE Adinolfi, A Ascione, G Morelli, S Lastoria, L Altucci, C Pedone, M Galdiero · Ultraschall in der Medizin - European Journal of Ultrasound · Ausgabe 08/2016

DOI 10.1055/s-0036-1587823

Bibliografische Angaben

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Autor:innenL Rinaldi, G Franci, V Folliero, L Palomba, R Isticato, C Zannella, R Di Francia, I De Sio, LE Adinolfi, A Ascione, G Morelli, S Lastoria, L Altucci, C Pedone, M Galdiero
ZeitschriftUltraschall in der Medizin - European Journal of Ultrasound
Ausgabe08/2016
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Purpose: We use an innovative method, known as sonoporation, to induce the expression of silenced gene in liver cancer cells (HepG2), such as (but nit restricted to) TRAIL in a specific manner. Aim of the project is the re-activation of silenced apoptotic pathway in liver cancer models, using diagnostic microbubble synovial as plasmidic gene delivery. Material and methods: HepG2 ATCC were used to assess all the expe…

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L Rinaldi, G Franci, V Folliero, L Palomba, R Isticato, C Zannella, R Di Francia, I De Sio, LE Adinolfi, A Ascione, G Morelli, S Lastoria, L Altucci, C Pedone, M Galdiero (2016) Sonoporation by microbubbles as gene therapy approach for liver cancer. Ultraschall in der Medizin - European Journal of Ultrasound (08). https://doi.org/10.1055/s-0036-1587823

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