CareLit · DOI-Nachweis · Pneumologie
STAT3-gain of function mutation as a cause of severe bronchiectasis and multi-organ autoimmunity; A case report
DOI 10.1055/s-0036-1592253
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Autor:innenT Khoury, R Kuint, V Molho-Pessach, Y Ramot, A Abu Rmeileh, O Elpeleg, N Berkman, A Zlotogorski, Y Ilan
ZeitschriftPneumologie
Ausgabe10/2016
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Signal transducer and activator of transcription 3 (STAT3) is a member of a family of proteins involved in the regulation of inflammation, differentiation, proliferation and survival. Loss or gain-of-function mutations in STAT3 lead to infectious and autoimmune complications. Recently, STAT3 gain-of-function mutations have been associated with the development of a multi-organ autoimmune syndrome. Case pr…
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Zitierempfehlung
T Khoury, R Kuint, V Molho-Pessach, Y Ramot, A Abu Rmeileh, O Elpeleg, N Berkman, A Zlotogorski, Y Ilan (2016) STAT3-gain of function mutation as a cause of severe bronchiectasis and multi-organ autoimmunity; A case report. Pneumologie (10). https://doi.org/10.1055/s-0036-1592253
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