CareLit · DOI-Nachweis · Pneumologie
CHI25243, a novel potent inhaled inhibitor of neutrophil elastase for the treatment of bronchiectasis and other chronic inflammatory lung disease
DOI 10.1055/s-0036-1592255
Bibliografische Angaben
Nachweis in CareLit
Autor:innenC Carnini, D Miglietta, V Puviani, MA Calderazzo, H Finch, C Fox, M Fitzgerald, R Patacchini, M Civelli, G Villetti
ZeitschriftPneumologie
Ausgabe10/2016
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Neutrophil elastase (NE) is a key proteolytic enzyme implicated in the pathogenesis and progression of chronic neutrophil-driven inflammatory lung diseases, including bronchiectasis, cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD). A number of clinical observations indicate that targeting NE might be beneficial for treating such inflammatory lung diseases. Here we studied the pharmacological pr…
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Zitierempfehlung
C Carnini, D Miglietta, V Puviani, MA Calderazzo, H Finch, C Fox, M Fitzgerald, R Patacchini, M Civelli, G Villetti (2016) CHI25243, a novel potent inhaled inhibitor of neutrophil elastase for the treatment of bronchiectasis and other chronic inflammatory lung disease. Pneumologie (10). https://doi.org/10.1055/s-0036-1592255
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