CareLit · DOI-Nachweis · Geburtshilfe und Frauenheilkunde
Prurified anti-trophoblast antibodies (ATAB) suppress the secretion of human Chorionic Gonadotropin (hCG) and stimulate that of Plaminogen-Activator-Inhibitor Type 1 (PAI-1) in JEG-3 cells in vitro
DOI 10.1055/s-0036-1592760
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Nachweis in CareLit
Autor:innenY Ye, M Vogel, P Burger, N Rogenhofer, S Mahner, U Jeschke, CJ Thaler, V von Schönfeldt
ZeitschriftGeburtshilfe und Frauenheilkunde
Ausgabe10/2016
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: ATAB are significantly more prevalent in recurrent miscarriage (RM) patients compared to controls1. Sera of ATAB-positive RM patients inhibit hCG secretion by JEG-3 cells in vitro and show higher concentrations of PAI-1 compared to ATAB-negative sera and healthy controls. We investigated the effect of purified IgGs from RM patients on the hCG and PAI-1 production of JEG-3 cells to further elucidate the p…
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Zitierempfehlung
Y Ye, M Vogel, P Burger, N Rogenhofer, S Mahner, U Jeschke, CJ Thaler, V von Schönfeldt (2016) Prurified anti-trophoblast antibodies (ATAB) suppress the secretion of human Chorionic Gonadotropin (hCG) and stimulate that of Plaminogen-Activator-Inhibitor Type 1 (PAI-1) in JEG-3 cells in vitro. Geburtshilfe und Frauenheilkunde (10). https://doi.org/10.1055/s-0036-1592760
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