CareLit · DOI-Nachweis · Klinische Pädiatrie
Radiosensitizing effect of 5-aza-2'-deoxycytidin in human glioblastoma cells
DOI 10.1055/s-0036-1593551
Bibliografische Angaben
Nachweis in CareLit
Autor:innenI Patties, M Frisman, E Kendzia, F Menzel, F Gaunitz, RD Kortmann, A Glasow
ZeitschriftKlinische Pädiatrie
Ausgabe11/2016
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Glioblastoma multiforme represents the most aggressive brain tumor. Its high infiltration rate and resistance to current treatment protocols results in a median survival of only 15 months following surgical removal and standard therapy. Epigenetic modulators have been shown to inhibit the growth of IDH-mutant glioma cells and may modulate DNA repair. Here, we analyzed the combined effect of the methyltransferase inh…
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Zitierempfehlung
I Patties, M Frisman, E Kendzia, F Menzel, F Gaunitz, RD Kortmann, A Glasow (2016) Radiosensitizing effect of 5-aza-2'-deoxycytidin in human glioblastoma cells. Klinische Pädiatrie (11). https://doi.org/10.1055/s-0036-1593551
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