CareLit · DOI-Nachweis · Klinische Pädiatrie
Next-generation immunogenic dendritic cell vaccines achieve a danger signaling and T cell-driven eradication of high-grade glioma
DOI 10.1055/s-0036-1593558
Bibliografische Angaben
Nachweis in CareLit
Autor:innenAD Garg, L Vandenberk, C Koks, T Verschuere, SW Van Gool, P Agostinis
ZeitschriftKlinische Pädiatrie
Ausgabe11/2016
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Two decades of translational research substantiates the promise of dendritic cell (DC)-based immunotherapy. Of the four malignancies mostly targeted with clinical DC immunotherapy, high-grade glioma (HGG) has shown the highest susceptibility. However, HGG-induced immunosuppression is an anti-immunotherapy roadblock as evident by the observation that HGG may fail to respond to CTLA-4 or IDO1 immune-checkpoint blockad…
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Zitierempfehlung
AD Garg, L Vandenberk, C Koks, T Verschuere, SW Van Gool, P Agostinis (2016) Next-generation immunogenic dendritic cell vaccines achieve a danger signaling and T cell-driven eradication of high-grade glioma. Klinische Pädiatrie (11). https://doi.org/10.1055/s-0036-1593558
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