CareLit · DOI-Nachweis · Klinische Pädiatrie
PI3K-mediated signalling in Glioblastoma
DOI 10.1055/s-0036-1593559
Bibliografische Angaben
Nachweis in CareLit
Autor:innenJ Langhans, L Schneele, N Trenkler, G Karpel-Massler, L Nonnenmacher, MD Siegelin, S Zhou, ME Halatsch, KM Debatin, MA Westhoff
ZeitschriftKlinische Pädiatrie
Ausgabe11/2016
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Glioblastoma, or Glioblastoma multiforme (GBM), is among the most malevolent and difficult to treat malignancies. The patients' life expectancy barely exceeds one year post-diagnosis, despite aggressive therapeutic intervention, consisting of maximal surgical removal, followed by courses of radio- and chemotherapy. Modulation of the PI3K/Akt/mTOR pathway, which exhibits high activity in almost 90% of all GBM, has lo…
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Zitierempfehlung
J Langhans, L Schneele, N Trenkler, G Karpel-Massler, L Nonnenmacher, MD Siegelin, S Zhou, ME Halatsch, KM Debatin, MA Westhoff (2016) PI3K-mediated signalling in Glioblastoma. Klinische Pädiatrie (11). https://doi.org/10.1055/s-0036-1593559
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