CareLit · DOI-Nachweis · Klinische Pädiatrie
Influence of MAPK-signaling on the temozolomide and nimustine induced apoptosis in glioma cells
DOI 10.1055/s-0036-1593562
Bibliografische Angaben
Nachweis in CareLit
Autor:innenM Christmann, R Meise, B Kaina, M Tomicic
ZeitschriftKlinische Pädiatrie
Ausgabe11/2016
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The outcome of cancer therapy strongly depends on the complex network of signaling pathways, including transcription factor activation following drug exposure. Here we assessed whether and how the MAP kinase (MAPK) cascade and its downstream target, the transcription factor AP-1, influence the sensitivity of malignant glioma cells to the anticancer drugs temozolomide (TMZ) and nimustine (ACNU). Activation of the MAP…
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Zitierempfehlung
M Christmann, R Meise, B Kaina, M Tomicic (2016) Influence of MAPK-signaling on the temozolomide and nimustine induced apoptosis in glioma cells. Klinische Pädiatrie (11). https://doi.org/10.1055/s-0036-1593562
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