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Expression of chemokines, metalloproteinases and cyclooxygenase in human synoviocytes by different Borrelia burgdorferi isolates

SK Singh, V Bar, U Samfas, H Morbach, MA Frosch, C Faber, HJ Girschick · Aktuelle Rheumatologie · Ausgabe 11/2003

DOI 10.1055/s-2003-45083

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Autor:innenSK Singh, V Bar, U Samfas, H Morbach, MA Frosch, C Faber, HJ Girschick
ZeitschriftAktuelle Rheumatologie
Ausgabe11/2003
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

To reveal the mechanisms of leukocyte chemoattraction and tissue distruction in Lyme disease, we investigated chemokine, metalloproteinase (MMP) and cyclooxygenase (COX2) expression in human synoviocytes (SC) exposed to different Borrelia burgdorferi (Bb) isolates (Geho, B31). Synoviocytes were infected for 12 hrs, 1 day, 2, 3 and 5 days as were controls. Semiquantitative RT-PCR was used to assess the relative chemo…

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SK Singh, V Bar, U Samfas, H Morbach, MA Frosch, C Faber, HJ Girschick (2003) Expression of chemokines, metalloproteinases and cyclooxygenase in human synoviocytes by different Borrelia burgdorferi isolates. Aktuelle Rheumatologie (11). https://doi.org/10.1055/s-2003-45083

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