CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Cytokine blockade inhibits hepatic TIMP-1 expression and upregulates MMP-9 in toxic liver injury
DOI 10.1055/s-2004-816044
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Autor:innenA Geier, CG Dietrich, M Roderfeld, B Jansen, C Gartung, S Matern, E Roeb
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe02/2004
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aims: TIMP-1, the most important endogenous inhibitor of many matrix metalloproteinases, plays an important role in the pathogenesis of liver fibrosis and may represent an effective therapeutic target in the design of anti-fibrotic strategies for ch ronic liver disease. Male Sprague-Dawley rats were treated with CCl4 in the presence and absence of specific cytokine inhibitors. Methods and Results: Toxic liver injury…
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Zitierempfehlung
A Geier, CG Dietrich, M Roderfeld, B Jansen, C Gartung, S Matern, E Roeb (2004) Cytokine blockade inhibits hepatic TIMP-1 expression and upregulates MMP-9 in toxic liver injury. Zeitschrift für Gastroenterologie (02). https://doi.org/10.1055/s-2004-816044
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