CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Effects of N-acetylcysteine and L-Cysteine on TGF-beta Signaling in Culture-activated Hepatic Stellate Cells
DOI 10.1055/s-2004-816049
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Nachweis in CareLit
Autor:innenS Meurer, B Lahme, R Weiskirchen, AM Gressner
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe02/2004
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Due to its profibrogenic actions, TGF-beta1 and the subsequent steps of the TGF-beta1 induced signaling cascade are prefered targets for antifibrogenic therapies. The fact that Smad-dependent TGF-beta signaling is modulated by reactive oxygen species (ROS) prompted us to investigate the influence of L-cysteine and its derivative N-acetylcysteine (NAC), a scavenger of ROS and precursor of glutathion, on TGF-beta sign…
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Zitierempfehlung
S Meurer, B Lahme, R Weiskirchen, AM Gressner (2004) Effects of N-acetylcysteine and L-Cysteine on TGF-beta Signaling in Culture-activated Hepatic Stellate Cells. Zeitschrift für Gastroenterologie (02). https://doi.org/10.1055/s-2004-816049
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