CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
IGF-I receptor-dependent mitogenic effect of platelet- derived growth factor in rat liver myofibroblasts
DOI 10.1055/s-2004-816051
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Autor:innenR Novosyadlyy, G Ramadori, JG Scharf
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe02/2004
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Background and aims: Insulin-like growth factor-I (IGF-I) is a potent mitogen for rat liver MF. Both IGF-I and its specific receptor (IGF-IR) are constitutively expressed in MF, possibly contributing to liver fibrogenesis via an autocrine loop. Since IGF-I is known as a progression factor for the growth-promoting effects of platelet-derived growth factor (PDGF) in many cell types, the aim of this work was to study t…
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Zitierempfehlung
R Novosyadlyy, G Ramadori, JG Scharf (2004) IGF-I receptor-dependent mitogenic effect of platelet- derived growth factor in rat liver myofibroblasts. Zeitschrift für Gastroenterologie (02). https://doi.org/10.1055/s-2004-816051
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