CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
IFN-γ signaling induces expression of Smad7 in hepatic stellate cells
DOI 10.1055/s-2004-816053
Bibliografische Angaben
Nachweis in CareLit
Autor:innenH Weng, AM Gressner, S Dooley
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe02/2004
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
TGF-b is a strong activator of hepatic stellate cells (HSC) and strategies targeting TGF-b signaling appear promising for antifibrotic therapies. IFN-g counteracts TGF-β effects and provides a beneficial anti-fibrotic influence. Studies regarding the effect of IFN-g on patients with hepatic fibrosis and molecular details of its impact on HSC are still lacking. Therefore, we investigated the role of IFN-γ on patients…
Zitieren
Zitierempfehlung
H Weng, AM Gressner, S Dooley (2004) IFN-γ signaling induces expression of Smad7 in hepatic stellate cells. Zeitschrift für Gastroenterologie (02). https://doi.org/10.1055/s-2004-816053
Mit CareLit weiterarbeiten