CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The role of Smad signaling in bile duct ligation induced fibrogenesis in rat
DOI 10.1055/s-2004-816070
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Autor:innenJ Hamzavi, H Seyhan, AM Gressner, S Dooley
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe02/2004
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
TGF- β1 has1s a central role in the fibrogenic response to injury in many organs, including the liver. Only little in vivo information is currently available regarding the impact of intracellular TGF-β signal transducers in fibrogenesis. Pathway restricted Smads2/3 are activated by ligand dependent phosphorylation through TGF-β receptor I. Phosphorylated Smads2/3 subsequently heterodimerize with Smad4 and form a tra…
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Zitierempfehlung
J Hamzavi, H Seyhan, AM Gressner, S Dooley (2004) The role of Smad signaling in bile duct ligation induced fibrogenesis in rat. Zeitschrift für Gastroenterologie (02). https://doi.org/10.1055/s-2004-816070
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