CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
A silencer element in the first intron of the glutamine synthetase gene and its role in hepatocellular expression
DOI 10.1055/s-2004-816082
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Autor:innenF Gaunitz, K Heise, R Gebhardt
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe02/2004
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
The enzyme glutamine synthetase (GS) ranks as one of the most remarkable glucocorticoid-inducible mammalian genes. In many cells the synthetic glucocorticoid dexamethasone (Dex) increases GS expression severalfold. The response is mediated by a cellular glucocorticoid receptor (GR) that interacts with glucocorticoid responsive elements (GREs). In the rat gene it was demonstrated that two GREs are responsible for the…
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Zitierempfehlung
F Gaunitz, K Heise, R Gebhardt (2004) A silencer element in the first intron of the glutamine synthetase gene and its role in hepatocellular expression. Zeitschrift für Gastroenterologie (02). https://doi.org/10.1055/s-2004-816082
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