CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The Export Pump MRP4 (ABCC4) is Localized to the Basolateral Membrane of Hepatocytes and Mediates Cotransport of Reduced Glutathione with Bile Salts
DOI 10.1055/s-2004-816095
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Nachweis in CareLit
Autor:innenM Rius, AT Nies, J Hummel-Eisenbeiss, G Jedlitschky, D Keppler
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe02/2004
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The liver is the major source of reduced glutathione which is released predominantly across the basolateral (sinusoidal) membrane into the blood circulation and serves as the principal source of plasma GSH, cysteine, and cystine. The transport protein mediating the efflux of GSH across the basolateral membrane of human hepatocytes has not been identified so far. We have localized the multidrug resistance protein 4 (…
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Zitierempfehlung
M Rius, AT Nies, J Hummel-Eisenbeiss, G Jedlitschky, D Keppler (2004) The Export Pump MRP4 (ABCC4) is Localized to the Basolateral Membrane of Hepatocytes and Mediates Cotransport of Reduced Glutathione with Bile Salts. Zeitschrift für Gastroenterologie (02). https://doi.org/10.1055/s-2004-816095
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