CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Activation of Caspases in HepG2 Cells is Dispensable for Cytokine-mediated Apoptosis Induced by either TNF, TRAIL or Agonistic anti-CD95 Antibody
DOI 10.1055/s-2004-816172
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Autor:innenG Dünstl, G Künstle, C Schlaeger, T Meergans, A Wendel
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe02/2004
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Actinomycin D-sensitized HepG2 cells are highly susceptible to induction of apoptosis via stimulation of death receptors (TNF-R1, CD95 and TRAIL receptor). We showed that the pan-caspase inhibitor zVADfmk conferred complete protection of HepG2 cells against apoptosis induced by TNFalpha or agonistic anti-CD95 antibody 1. Here we provide evidence that prevention of apoptosis by zVADfmk is not due to inhibition of cas…
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Zitierempfehlung
G Dünstl, G Künstle, C Schlaeger, T Meergans, A Wendel (2004) Activation of Caspases in HepG2 Cells is Dispensable for Cytokine-mediated Apoptosis Induced by either TNF, TRAIL or Agonistic anti-CD95 Antibody. Zeitschrift für Gastroenterologie (02). https://doi.org/10.1055/s-2004-816172
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