CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Comprehensive analysis of the intrahepatic virus-specific CD8+ T-cell response during chronic hepatitis C virus infection
DOI 10.1055/s-2004-816176
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Autor:innenC Neumann-Haefelin, HC Spangenberg, E Panther, C Steiger, N Kersting, F von Weizsäcker, HE Blum, R Thimme
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe02/2004
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
In order to define the actual breadth and magnitude of the virus-specific CD8+-T-cell response during chronic hepatitis C virus infection, we have studied this response in the liver and blood by using a set of 441 overlapping peptides spanning the entire HCV polyprotein. Peptides identified in screening ELISPOTs were further tested by intracellular IFNγ staining. Multispecific virus-specific CD8+-T-cell responses we…
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Zitierempfehlung
C Neumann-Haefelin, HC Spangenberg, E Panther, C Steiger, N Kersting, F von Weizsäcker, HE Blum, R Thimme (2004) Comprehensive analysis of the intrahepatic virus-specific CD8+ T-cell response during chronic hepatitis C virus infection. Zeitschrift für Gastroenterologie (02). https://doi.org/10.1055/s-2004-816176
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