CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
CD8+ T cell tolerance induced by liver sinusoidal endothelial cells depends on ICOS/ICOSL interactions
DOI 10.1055/s-2004-816197
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Autor:innenL Diehl, G Wingender, A Hutloff, R Kroczek, S Porcelli, A Limmer, PA Knolle
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe02/2004
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The liver is know to have an immunological function and is involved in systemic peripheral tolerance. We have previously demonstrated that liver sinusoidal endothelial cells (LSEC), a new class of organ resident APC, can induce antigen specific T cell tolerance in vitro and in vivo. However, the molecular mechanisms underlying this observation remained unresolved. Here we show that the triggering of the inducible co…
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Zitierempfehlung
L Diehl, G Wingender, A Hutloff, R Kroczek, S Porcelli, A Limmer, PA Knolle (2004) CD8+ T cell tolerance induced by liver sinusoidal endothelial cells depends on ICOS/ICOSL interactions. Zeitschrift für Gastroenterologie (02). https://doi.org/10.1055/s-2004-816197
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