CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Gemcitabine treatment enhances the activity of deoxycytidine kinase in periferial lymphocytes of patients with pancreatic cancer
DOI 10.1055/s-2004-827078
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Nachweis in CareLit
Autor:innenE Vegh, Y Al-Farhat, T Spasokoukotskaja, G Keszler, T Nagy, M Staub, G Bodoky
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe05/2004
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Gemcitabine (2', 2'-difluorodeoxycytidine, dFdC) has shown significant preclinical and clinical activity against several human solid tumors, including pancreatic cancer. Deoxycytidine kinase (dCK) is the key enzyme in the bioactivation of gemcitabine. In the present work the activity of dCK prior to and following gemcitabine treatment in patients with advanced pancreatic cancer has been evaluated. Meth…
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Zitierempfehlung
E Vegh, Y Al-Farhat, T Spasokoukotskaja, G Keszler, T Nagy, M Staub, G Bodoky (2004) Gemcitabine treatment enhances the activity of deoxycytidine kinase in periferial lymphocytes of patients with pancreatic cancer. Zeitschrift für Gastroenterologie (05). https://doi.org/10.1055/s-2004-827078
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