CareLit · DOI-Nachweis · Klinische Pädiatrie
Identification of proteins differentially expressed upon neurotrophin receptor activation using DIGE and MALDI-MS
DOI 10.1055/s-2004-828547
Bibliografische Angaben
Nachweis in CareLit
Autor:innenO Apostolov, B Sitek, K Pfeiffer, K Stühler, HE Meyer, A Eggert, A Schramm
ZeitschriftKlinische Pädiatrie
Ausgabe05/2004
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Activation of the neurotrophin receptor TrkA by its ligand NGF mediates growth inhibition and differentiation of neuroblastoma cells, whereas TrkB/BDNF signaling promotes proliferation and therapy resistance. Nonetheless, TrkA and TrkB exhibit a high level of sequence homology and use overlapping signaling pathways. To identify novel effector molecules contributing to the characteristic phenotypes of TrkA- and TrkB-…
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Zitierempfehlung
O Apostolov, B Sitek, K Pfeiffer, K Stühler, HE Meyer, A Eggert, A Schramm (2004) Identification of proteins differentially expressed upon neurotrophin receptor activation using DIGE and MALDI-MS. Klinische Pädiatrie (05). https://doi.org/10.1055/s-2004-828547
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