CareLit · DOI-Nachweis · Klinische Pädiatrie
Quantification of drug induced mitochondria- and caspase-mediated apoptosis signaling in primary leukemia cells by flow cytometry
DOI 10.1055/s-2004-828560
Bibliografische Angaben
Nachweis in CareLit
Autor:innenSM Eckhoff, LH Meyer, KM Debatin, K Stahnke
ZeitschriftKlinische Pädiatrie
Ausgabe05/2004
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Analysis of apoptosis pathways in primary leukemia cells for assessment of drug sensitivity or resistance has been hampered by the lack of convenient methods for measurement of activated apoptosis signaling. Caspase activation and mitochondrial alterations are key components of apoptosis signal transduction. We developed and characterized a flow cytometric method for combined measurement of caspase activation by cle…
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Zitierempfehlung
SM Eckhoff, LH Meyer, KM Debatin, K Stahnke (2004) Quantification of drug induced mitochondria- and caspase-mediated apoptosis signaling in primary leukemia cells by flow cytometry. Klinische Pädiatrie (05). https://doi.org/10.1055/s-2004-828560
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