CareLit · DOI-Nachweis · Klinische Pädiatrie
Genomic structure and nucleotide sequence of AML1-ETO fusion genes in children with acute myeloid leukemia
DOI 10.1055/s-2004-828564
Bibliografische Angaben
Nachweis in CareLit
Autor:innenC Gall, T Langer, M Metzler, S Viehmann, J Harbott, D Reinhardt, U Creutzig, JD Beck, W Rascher
ZeitschriftKlinische Pädiatrie
Ausgabe05/2004
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: The human ETO gene at 8q22 is a common fusion partner of the AML1 gene at 21q22, resulting in the translocation t(8;21)(q22;q22). The AML1 gene spans more than 340kb whereas ETO only spans 150kb. Respectively three breakpoint cluster regions (BCRs) have been identified in intron 5 of AML1 and intron 1b of ETO. In infants with AML 11% present a t(8;21) at diagnosis. Methods: In this study we investigated…
Zitieren
Zitierempfehlung
C Gall, T Langer, M Metzler, S Viehmann, J Harbott, D Reinhardt, U Creutzig, JD Beck, W Rascher (2004) Genomic structure and nucleotide sequence of AML1-ETO fusion genes in children with acute myeloid leukemia. Klinische Pädiatrie (05). https://doi.org/10.1055/s-2004-828564
Mit CareLit weiterarbeiten