CareLit · DOI-Nachweis · Klinische Pädiatrie
Combined use of 4-color flow cytometry and real-time PCR to detect minimal residual disease (MRD) in childhood acute lymphoblastic leukemia
DOI 10.1055/s-2004-828578
Bibliografische Angaben
Nachweis in CareLit
Autor:innenG Kerst, H Kreyenberg, E Koscielniak, G Dückers, C Niemeyer, I Müller, K Schilbach, R Handgretinger, PG Schlegel, D Niethammer, P Bader
ZeitschriftKlinische Pädiatrie
Ausgabe05/2004
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: MRD detection in ALL patients is commonly performed by PCR amplification of clone-specific immunoglobulin and T-cell receptor gene rearrangements. Despite its high sensitivity, PCR amplification carries the risk of false-negative results due to clonal evolution and can not yet be applied to all patients. Therefore, the additional use of a second method seems feasible. Methods: Flow cytometric analysis…
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Zitierempfehlung
G Kerst, H Kreyenberg, E Koscielniak, G Dückers, C Niemeyer, I Müller, K Schilbach, R Handgretinger, PG Schlegel, D Niethammer, P Bader (2004) Combined use of 4-color flow cytometry and real-time PCR to detect minimal residual disease (MRD) in childhood acute lymphoblastic leukemia. Klinische Pädiatrie (05). https://doi.org/10.1055/s-2004-828578
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