CareLit · DOI-Nachweis · Klinische Pädiatrie
The human proto-oncoprotein AF4 interacts with the E3-ligases SIAH1 and SIAH2
DOI 10.1055/s-2004-828584
Bibliografische Angaben
Nachweis in CareLit
Autor:innenS Moritz, A Bursen, T Dingermann, R Marschalek
ZeitschriftKlinische Pädiatrie
Ausgabe05/2004
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The human proto-oncoprotein AF4 was identified to interact with SIAH1 and SIAH2. SIAH proteins belong to the family of ubiquitin E3 ligases that bind to specific target proteins and mediate their destruction via the proteasomal pathway. Therefore, SIAH target proteins are strictly controlled in their specific steady-state level and their turn-over rates. Currently known SIAH target proteins are e.g. DCC, OBF1, TIEG1…
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Zitierempfehlung
S Moritz, A Bursen, T Dingermann, R Marschalek (2004) The human proto-oncoprotein AF4 interacts with the E3-ligases SIAH1 and SIAH2. Klinische Pädiatrie (05). https://doi.org/10.1055/s-2004-828584
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