CareLit · DOI-Nachweis · Klinische Pädiatrie
NG2-expression as a marker for MRD: The molecule detected by moAb 7.1 can not be found on the surface of primitive CD34+ progenitor cells
DOI 10.1055/s-2004-828586
Bibliografische Angaben
Nachweis in CareLit
Autor:innenJ Neudenberger, A Rosemann, M Hotfilder, C Langebrake, D Reinhardt, J Vormoor
ZeitschriftKlinische Pädiatrie
Ausgabe05/2004
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The human homologue of the rat NG2 protein is being discussed as a potential marker for early minimal residual disease (MRD) detection in high risk 11q23-transformed leukemia. As recent studies have shown, the leukemic transformation can occure in CD34+ primitive stem/progenitor cells. Consequently a protein expressed on the leukemia initiating cell concurrent with the transformation, would be the key to early MRD d…
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Zitierempfehlung
J Neudenberger, A Rosemann, M Hotfilder, C Langebrake, D Reinhardt, J Vormoor (2004) NG2-expression as a marker for MRD: The molecule detected by moAb 7.1 can not be found on the surface of primitive CD34+ progenitor cells. Klinische Pädiatrie (05). https://doi.org/10.1055/s-2004-828586
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