CareLit · DOI-Nachweis · Klinische Pädiatrie
L-selectin expression defines a subpopulation of In vitro generated AML-reactive T-cells with superior anti-leukemic efficacy for adoptive immunotherapy
DOI 10.1055/s-2004-828590
Bibliografische Angaben
Nachweis in CareLit
Autor:innenMG Sauer, ME Ericson, BL Levine, CH June, BJ Weigel, K Welte, BR Blazar
ZeitschriftKlinische Pädiatrie
Ausgabe05/2004
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
To determine the mechanisms by which adopive immunotherapy with leukemia–reactive cytotoxic T-cells (CTLs) could reduce AML lethality, a novel technique was developed to track, both leukemic blasts and adoptively transferred CTLs independently and simultaneously in vivo. Starting with splenocytes from eGFP (enhanced green fluorescent protein) transgeneic mice AML-reactive CTLs were genarated in vitro. Stable transfe…
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Zitierempfehlung
MG Sauer, ME Ericson, BL Levine, CH June, BJ Weigel, K Welte, BR Blazar (2004) L-selectin expression defines a subpopulation of In vitro generated AML-reactive T-cells with superior anti-leukemic efficacy for adoptive immunotherapy. Klinische Pädiatrie (05). https://doi.org/10.1055/s-2004-828590
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