CareLit · DOI-Nachweis · Klinische Pädiatrie
Differential effects of TrkA or TrkB expression on DNA repair capacity might contribute to the genomic stability of SY5Y neuroblastoma cells
DOI 10.1055/s-2004-828594
Bibliografische Angaben
Nachweis in CareLit
Autor:innenJ Schulte, D Dobrzinski, S Kuhfittig-Kulle, E Feldmann, A Schramm, H Stephan, L Klein-Hitpass, W Havers, P Pfeiffer, A Eggert
ZeitschriftKlinische Pädiatrie
Ausgabe05/2004
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The capacity to repair DNA double strand breaks (DSB) is crucial for genomic stability. The non-homologous end-joining pathway (NHEJ) for DNA repair is an important caretaker of the mammalian genome. High expression of TrkA is associated with favorable prognosis of neuroblastoma and a lack of structural chromosomal changes, whereas TrkB is expressed on aggressive neuroblastomas with high genomic instability. We here…
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Zitierempfehlung
J Schulte, D Dobrzinski, S Kuhfittig-Kulle, E Feldmann, A Schramm, H Stephan, L Klein-Hitpass, W Havers, P Pfeiffer, A Eggert (2004) Differential effects of TrkA or TrkB expression on DNA repair capacity might contribute to the genomic stability of SY5Y neuroblastoma cells. Klinische Pädiatrie (05). https://doi.org/10.1055/s-2004-828594
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