CareLit · DOI-Nachweis · Klinische Pädiatrie
Differentiation of myeloid leukemia cells by HDAC-inhibitors
DOI 10.1055/s-2004-828595
Bibliografische Angaben
Nachweis in CareLit
Autor:innenS Schulze, B Busche, H Nau, D Eikel, L Schweigerer, O Witt
ZeitschriftKlinische Pädiatrie
Ausgabe05/2004
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Histone deacetylase (HDAC)-inhibitors are a new class of promising anti-cancer agents. Here we show that different structural classes of HDAC-inhibitors (butyric acid, apicidin, MS-275, SAHA, novel synthesized valproic acid derivatives) exhibit anti-proliferative and erythroid differentiation inducing activities in bcr/abl positive K562 myeloid leukemia cells. Inhibition of cell proliferation and erythroid different…
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Zitierempfehlung
S Schulze, B Busche, H Nau, D Eikel, L Schweigerer, O Witt (2004) Differentiation of myeloid leukemia cells by HDAC-inhibitors. Klinische Pädiatrie (05). https://doi.org/10.1055/s-2004-828595
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