CareLit · DOI-Nachweis · Klinische Pädiatrie
Comparison of clinical features of alveolar RMS with pax-fkhr fusion transcripts and their prognostic impact
DOI 10.1055/s-2004-828596
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Nachweis in CareLit
Autor:innenS Stegmaier, KL Schaeffer, C Poremba, B Kazanowska, E Hallmen, I Haug, J Treuner, I Leuschner, E Koscielniak
ZeitschriftKlinische Pädiatrie
Ausgabe05/2004
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The translocations t(2;13)(q35;q14) and t(1;13)(p36;q14) are associated with alveolar RMS, generating the chimeric genes pax3-fkhr and pax7-fkhr. To analyse their clinical relevance we examined tumor samples from pts registered in the CWS-86, -91, -96-studies by RT-PCR. We compared clinical characteristics and prognosis for 75 alveolar RMS pts with a detected translocation. 59 tumor samples were positive for pax3- (…
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Zitierempfehlung
S Stegmaier, KL Schaeffer, C Poremba, B Kazanowska, E Hallmen, I Haug, J Treuner, I Leuschner, E Koscielniak (2004) Comparison of clinical features of alveolar RMS with pax-fkhr fusion transcripts and their prognostic impact. Klinische Pädiatrie (05). https://doi.org/10.1055/s-2004-828596
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