CareLit · DOI-Nachweis · Klinische Pädiatrie
Doxorubicin reduces telomerase activity in a human Ewing-Xenograft tumor
DOI 10.1055/s-2004-828601
Bibliografische Angaben
Nachweis in CareLit
Autor:innenB Winter, C Lanvers-Kaminsky, S Koling, B Frodermann, Y Braun, KL Schäfer, RI Diallo, S Könemann, J Boos, N Willich, C Poremba, A Schuck
ZeitschriftKlinische Pädiatrie
Ausgabe05/2004
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aim: For its almost selective expression in human tumours telomerase is a promising target for cancer treatment. We evaluated the effects of doxorubicin (DOX) on telomerase in the human Ewing sarcoma cell line STA-ET-1 in vitro and in nude mice in vivo. Methods: In vitro toxicity was determined by the MTT-assay. Tumour xenografts were analysed for proliferation, necrosis, and apoptosis by MIB-, HE-staining and TUNEL…
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Zitierempfehlung
B Winter, C Lanvers-Kaminsky, S Koling, B Frodermann, Y Braun, KL Schäfer, RI Diallo, S Könemann, J Boos, N Willich, C Poremba, A Schuck (2004) Doxorubicin reduces telomerase activity in a human Ewing-Xenograft tumor. Klinische Pädiatrie (05). https://doi.org/10.1055/s-2004-828601
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