CareLit · DOI-Nachweis · Zentralblatt für Gynäkologie
Cellular immunotherapy in late stage breast cancer patients with reactivated autologous Memory T-cells (MTC) derived from bone marrow (BM) (Phase-I trail)
DOI 10.1055/s-2004-828783
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Autor:innenK Ehlert, P Beckhove, IJ Diel, V Schirrmacher, A Schneeweiss, G Bastert, HJ Strittmatter, F Schuetz
ZeitschriftZentralblatt für Gynäkologie
Ausgabe06/2004
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
We have previously shown an enrichment of tumor-specific MTC in BM in 66% of breast cancer patients by using ELISpot-analysis. Upon specific restimulation with dendritic cells (DC) in vitro BM T cells exert specific effector functions like IFN-gamma production and cytotoxicity. Furthermore we have shown in NOD/Scid-mice that reactivated MTC are able to kill tumor cells by induction of apoptosis (Nature Med, 2001). T…
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Zitierempfehlung
K Ehlert, P Beckhove, IJ Diel, V Schirrmacher, A Schneeweiss, G Bastert, HJ Strittmatter, F Schuetz (2004) Cellular immunotherapy in late stage breast cancer patients with reactivated autologous Memory T-cells (MTC) derived from bone marrow (BM) (Phase-I trail). Zentralblatt für Gynäkologie (06). https://doi.org/10.1055/s-2004-828783
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