CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Lymphotoxin beta controls immunity in experimental colitis by regulation of splenic dendritic cell homing
DOI 10.1055/s-2004-831532
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Autor:innenTW Spahn, C Maaser, A Lügering, J Heidemann, H Herbst, W Domschke, T Kucharzik
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2004
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Lymphotoxin (LT) is a TNF family cytokine. Blocking of LTalpha(Α)1beta(Β)2–LTBreceptor (LTΒR) interactions prevents experimental colitis and other experimental autoimmune disease in mice, suggesting a potential treatment principle of human inflammatory bowel disease (IBD). Infection of mice with Citrobacter rodentium (C. r.) serves as an animal model for human infectious colitis induced by enteropathogen E. coli (EP…
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Zitierempfehlung
TW Spahn, C Maaser, A Lügering, J Heidemann, H Herbst, W Domschke, T Kucharzik (2004) Lymphotoxin beta controls immunity in experimental colitis by regulation of splenic dendritic cell homing. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-2004-831532
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