CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Different biological responses to chemotherapy of colon cancer may result in a similar clinical response
DOI 10.1055/s-2004-831658
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Nachweis in CareLit
Autor:innenM Bhonde, ML Hanski, M Notter, M Zeitz, C Hanski
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2004
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Irinotecan in combination with 5-FU is used as a „first line„ therapy for advanced colorectal cancer. We showed recently that the response to irinotecan in vitro is dependent on the p53 mutation status of the tumor: the p53wt colorectal cancer cell lines respond to treatment with a long-term arrest, the p53mut cells with a short term arrest followed by mitotic catastrophe and apoptosis. We investigated…
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Zitierempfehlung
M Bhonde, ML Hanski, M Notter, M Zeitz, C Hanski (2004) Different biological responses to chemotherapy of colon cancer may result in a similar clinical response. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-2004-831658
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