CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
p53 selective adenoviral vector for transgene expression and replication as a therapeutic tool for virotherapy of p53 altered cancers
DOI 10.1055/s-2004-831673
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Nachweis in CareLit
Autor:innenF Kühnel, L Zender, T Wirth, B Schulte, MP Manns, S Kubicka
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2004
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: A major obstacle of adenoviral cancer therapy is the tight restriction of therapeutic gene expression or viral replication to malignant cells. This study presents the bicistronic adenoviral vector Adp53dpR for gene therapy of tumor cells with altered p53-status. Methods/Results: First, a luciferase version of Adp53dpR-(Luc) was constructed including one cistron containing luciferase controlled by an artificial…
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Zitierempfehlung
F Kühnel, L Zender, T Wirth, B Schulte, MP Manns, S Kubicka (2004) p53 selective adenoviral vector for transgene expression and replication as a therapeutic tool for virotherapy of p53 altered cancers. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-2004-831673
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