CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
A novel approach in the treatment of neuroendocrine gastrointestinal tumors: targeting the epidermal growth factor receptor (EGFR) by gefitinib (ZD1839; Iressa)
DOI 10.1055/s-2004-831679
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Nachweis in CareLit
Autor:innenM Höpfner, A Sutter, B Gerst, M Zeitz, H Scherübl
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2004
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Therapeutic options to inhibit growth and further spread of metastatic NE tumor disease are still limited. Here, we demonstrate that targeting the EGFR-sensitive tyrosine kinase (TK) by the EGFR-TK inhibitor gefitinib may be a promising future approach for effective growth control of NE tumors. mRNA- and protein expression of EGFR and EGFR-transactivating insulin-like growth factor receptors of three NE tumor cell l…
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Zitierempfehlung
M Höpfner, A Sutter, B Gerst, M Zeitz, H Scherübl (2004) A novel approach in the treatment of neuroendocrine gastrointestinal tumors: targeting the epidermal growth factor receptor (EGFR) by gefitinib (ZD1839; Iressa). Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-2004-831679
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