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Combined antiangiogenic gene therapy with sflt and endostatin is highly effective in a rat model of hepatocellular carcinoma

F Graepler, B Verbeek, T Gräter, I Smirnow, HL Kong, D Schuppan, M Wehrmann, M Gregor, UM Lauer · Zeitschrift für Gastroenterologie · Ausgabe 08/2004

DOI 10.1055/s-2004-831698

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Autor:innenF Graepler, B Verbeek, T Gräter, I Smirnow, HL Kong, D Schuppan, M Wehrmann, M Gregor, UM Lauer
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2004
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

The multiplicity of regulators acting in the process of tumor angiogenesis offers diverse molecular targets for an antiangiogenic therapy. On the other hand, therapeutical attempts to antagonize one of these players could be equalized by upregulation of another proangiogenic factor leading to some kind of resistance to antiangiogenic therapy. A combination therapy addressing two or more angiogenic targets could ther…

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Zitierempfehlung

F Graepler, B Verbeek, T Gräter, I Smirnow, HL Kong, D Schuppan, M Wehrmann, M Gregor, UM Lauer (2004) Combined antiangiogenic gene therapy with sflt and endostatin is highly effective in a rat model of hepatocellular carcinoma. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-2004-831698

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