CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Regulatory T cells suppress virus-specific CD8+ T cells in chronically hepatitis C virus infected patients
DOI 10.1055/s-2004-831765
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Autor:innenT Boettler, HC Spangenberg, C Neumann-Haefelin, E Panther, F von Weizsäcker, HE Blum, R Thimme
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2004
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Introduction: Chronic hepatitis C virus (HCV) infection is characterized by a weak and dysfunctional virus-specific CD8+ T cell response. The mechanisms for this failure are not well understood. In this study, we analyzed the role of CD4+CD25+ regulatory T cells (Treg cells) in the suppression of HCV specific CD8+ T cell responses in chronically HCV infected patients. Methods: PBMCs were obtained from 10 chronically…
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Zitierempfehlung
T Boettler, HC Spangenberg, C Neumann-Haefelin, E Panther, F von Weizsäcker, HE Blum, R Thimme (2004) Regulatory T cells suppress virus-specific CD8+ T cells in chronically hepatitis C virus infected patients. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-2004-831765
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